Which regulation states the requirements and responsibilities for personnel who have access to nuclear weapons and systems?

• A. AFI 36-2605
• B. DoDI 8500.01
• C. DoDM 5210.42_AFMAN 13-501, Nuclear Weapons Personnel Reliability Program (PRP)
• D. AFMAN 33-201

Answer: (C)

Access to nuclear weapons and systems is governed by the Nuclear Weapons Personnel Reliability Program (PRP). The DoDM 5210.42, along with AFMAN 13-501, codifies the program’s requirements and responsibilities, ensuring only qualified personnel have access. It covers eligibility, background investigations, medical and psychological fitness, drug testing, and ongoing evaluation, plus the processes to grant, suspend, or revoke access. It also defines roles for commanders, security forces, PRP managers, medical staff, and security personnel to maintain reliability and accountability. This direct focus on who may access nuclear weapons and how that access is maintained is why this regulation is the correct choice. The other regulations address different areas such as fitness programs or information assurance, and do not establish PRP requirements for nuclear access.